Arizona Cardinals

ARI

Arizona Cardinals

11-7, 10-8 ATS

31

17

SF

San Francisco 49ers

12-7, 11-8 ATS

San Francisco 49ers

Media Consensus Picks

277 PicksMoneyline
Arizona Cardinals

ARI

+190

64%

64% predicted the Cardinals to win.

233 PicksSpread
Arizona Cardinals

ARI +5.5

-108

65%

65% predicted the Cardinals to cover the spread.

122 PicksOver/Under

Over 44.5

-115

57%

57% predicted the score to be over 44.5.

Best Sportsbook Odds


Arizona Cardinals
ARI
Team Performance
SF
San Francisco 49ers
Moneyline
11-7 (61%)OverallOverall12-7 (63%)
8-2 (80%)On RoadAt Home4-4 (50%)
6-1 (86%)As UnderdogAs Favorite8-6 (57%)
6-1 (86%)As Road UnderdogAs Home Favorite3-4 (43%)
Spread
10-8 (56%)OverallOverall11-8 (58%)
8-2 (80%)On RoadAt Home4-4 (50%)
6-1 (86%)As UnderdogAs Favorite7-7 (50%)
6-1 (86%)As Road UnderdogAs Home Favorite3-4 (43%)
Over/Under/Push
8-10 (44%)OverallOverall9-10 (47%)
4-6 (40%)On RoadAt Home4-4 (50%)
3-4 (43%)As UnderdogAs Favorite8-6 (57%)

What National Media Said

57% of national media analysts called the Cardinals victory.

Featured National Media Analyst
Gregg Rosenthal

Gregg Rosenthal

NFL Network

ARI

Arizona Cardinals

ARI -1

Under 46

Cardinals 23, 49ers 20

“I was all ready to lock up the Cardinals to win this game on the Around The NFL Podcast this week ... until Kyler Murray missed practice Wednesday with his ankle injury. Murray is capable of winning from the pocket even if he's not 100 percent, but A.J. Green is on the Reserve/COVID-19 list and DeAndre Hopkins' hamstring makes him a shaky proposition. The return of George Kittle gives Jimmy Garoppolo a chance, but an offense this dependent on Deebo Samuel making magic is hard to trust, especially with Samuel aggravating his calf injury.”...

November 4, 2021 via nfl.com

Featured National Media Analyst
Mike Florio

Mike Florio

ProFootballTalk

SF

San Francisco 49ers

SF +1

49ers 24, Cardinals 20

“The 49ers remain in desperation territory, and Kyler Murray remains banged up.”...

November 4, 2021 via profootballtalk.nbcsports.com

Featured National Media Analyst
Michael David Smith

Michael David Smith

ProFootballTalk

ARI

Arizona Cardinals

ARI -1

Cardinals 28, 49ers 23

“The Cardinals should bounce back from a tough loss to the Packers last Thursday and get back on the winning track against a 49ers team that just isn’t consistent enough.”...

November 4, 2021 via profootballtalk.nbcsports.com

Swipe left to see more expert picks


Arizona Cardinals

What Cardinals Insiders Said

67% of team insiders called the Cardinals victory.

Featured Cardinals Insider
Josh Weinfuss

Josh Weinfuss

ESPN NFL Nation

ARI

Arizona Cardinals

ARI +1

Over 45

Cardinals 27, 49ers 20

“Cardinals quarterback Kyler Murray will throw for 300 yards and three touchdowns in a big divisional win. He will likely have his mobility limited to some degree, which will lead to him throwing the ball”...

November 5, 2021 via espn.com

Featured Cardinals Insider
Blake Murphy

Blake Murphy

Revenge of the Birds

SF

Arizona Cardinals

ARI +2.5

Under 44.5

November 6, 2021

Featured Cardinals Insider
Jess Root

Jess Root

Sportsbook Wire

ARI

Arizona Cardinals

ARI +2.5

Under 44.5

November 6, 2021

Swipe left to see more expert picks


San Francisco 49ers

What 49ers Insiders Said

0% of team insiders called the Cardinals victory.

Featured 49ers Insider
Nick Wagoner

Nick Wagoner

ESPN NFL Nation

SF

San Francisco 49ers

SF -1

Under 45

49ers 23, Cardinals 20

“These teams met less than a month ago, but a lot has changed on both sides. Cardinals QB Kyler Murray and receiver DeAndre Hopkins are dealing with injuries, receiver A.J. Green is on the COVID-19 list and defensive end J.J. Watt is out for the season. The Niners, meanwhile, expect to have kicker Robbie Gould and tight end George Kittle back from their injuries, and quarterback Jimmy Garoppolo will be available this time around. The first meeting was decided by seven points, and this one should be similarly close, with the team that handles attrition better being the likely winner.”...

November 5, 2021 via espn.com

Featured 49ers Insider
Alex Byrne

Alex Byrne

Fourth and Nine

SF

San Francisco 49ers

SF -2.5

Under 45.5

November 5, 2021

Swipe left to see more expert picks


Top-Ranked Expert Picks

Best performing analysts in each category this season.

49ers Overall Experts

Jess Root

30-14-1 (68%)

ARI

Kyle Silagyi

31-13-1 (70%)

ARI

Christopher Dunnells

27-12-0 (69%)

ARI
49ers Moneyline Experts

Jess Root

13-2-0 (87%)

ARI

Brenden Ertle

11-4-0 (73%)

ARI

Zach Lowder

11-3-0 (79%)

ARI
49ers Spread Experts

Craig Miller

11-3-1 (79%)

ARI +0.5

Jess Root

11-3-1 (79%)

ARI +2.5

Pete Sweeney

11-3-1 (79%)

ARI -1.5
49ers Over/Under Experts

Andrew Reid

11-3-0 (79%)

Under 45.5

Bryan Davis

10-5-0 (67%)

Over 45.5

Aaron Quinn

9-4-0 (69%)

Over 44.5
Cardinals Overall Experts

Michael Regan

21-3-0 (88%)

ARI

Michael Flores

22-8-0 (73%)

SF

John Whiticar

30-15-0 (67%)

ARI
Cardinals Moneyline Experts

Michael Regan

11-1-0 (92%)

ARI

J Andrews

9-5-0 (64%)

SF

Brandan Schulze

9-4-0 (69%)

ARI
Cardinals Spread Experts

Michael Regan

10-2-0 (83%)

ARI +3.5

Brent Sobleski

11-4-0 (73%)

ARI -1

HC Green

11-4-0 (73%)

ARI -1.5
Cardinals Over/Under Experts

Michael Flores

9-1-0 (90%)

Over 43.5

Warren Ludford

11-4-0 (73%)

Over 45.5

John Whiticar

11-4-0 (73%)

Over 44.5

Top-Ranked Staff Consensus Picks

Consensus staff picks from the best performing outlets this season.

NFL Network

190-176-0 (52%)

Matchup Performance

ARI (55%)Moneyline
ARI +5.5 (100%)Spread
No O/U PicksTotal
CBS Sports

232-248-0 (48%)

Matchup Performance

ARI (25%)Moneyline
ARI +5.5 (25%)Spread
No O/U PicksTotal
USA Today Sports

236-183-1 (56%)

Matchup Performance

ARI (71%)Moneyline
ARI +5.5 (57%)Spread
No O/U PicksTotal
Bleacher Report

90-88-0 (51%)

Matchup Performance

ARI (0%)Moneyline
ARI +5.5 (83%)Spread
No O/U PicksTotal