Arizona Cardinals

ARI

Arizona Cardinals

31

17

SF

San Francisco 49ers

San Francisco 49ers

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Media Consensus Picks

277 PicksMoneyline
Arizona Cardinals

ARI

+190

64%

64% predicted the Cardinals to win.

233 PicksSpread
Arizona Cardinals

ARI +5.5

-108

65%

65% predicted the Cardinals to cover the spread.

122 PicksOver/Under

Over 44.5

-115

57%

57% predicted the score to be over 44.5.

Best Sportsbook Odds


What National Media Said

57% of national media analysts called the Cardinals victory.

Featured National Media Analyst
Gregg Rosenthal

Gregg Rosenthal

NFL Network

ARI

Arizona Cardinals

ARI -1

Under 46

Cardinals 23, 49ers 20

“I was all ready to lock up the Cardinals to win this game on the Around The NFL Podcast this week ... until Kyler Murray missed practice Wednesday with his ankle injury. Murray is capable of winning from the pocket even if he's not 100 percent, but A.J. Green is on the Reserve/COVID-19 list and DeAndre Hopkins' hamstring makes him a shaky proposition. The return of George Kittle gives Jimmy Garoppolo a chance, but an offense this dependent on Deebo Samuel making magic is hard to trust, especially with Samuel aggravating his calf injury.”...

November 4, 2021 via nfl.com

Featured National Media Analyst

SF

San Francisco 49ers

SF -1

Under 45

49ers 23, Cardinals 20

“These teams met less than a month ago, but a lot has changed on both sides. Cardinals QB Kyler Murray and receiver DeAndre Hopkins are dealing with injuries, receiver A.J. Green is on the COVID-19 list and defensive end J.J. Watt is out for the season. The Niners, meanwhile, expect to have kicker Robbie Gould and tight end George Kittle back from their injuries, and quarterback Jimmy Garoppolo will be available this time around. The first meeting was decided by seven points, and this one should be similarly close, with the team that handles attrition better being the likely winner.”...

November 5, 2021 via espn.com

Featured National Media Analyst

ARI

Arizona Cardinals

ARI +1

Over 45

Cardinals 27, 49ers 20

“Cardinals quarterback Kyler Murray will throw for 300 yards and three touchdowns in a big divisional win. He will likely have his mobility limited to some degree, which will lead to him throwing the ball”...

November 5, 2021 via espn.com

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Arizona Cardinals

What Cardinals Insiders Said

67% of team insiders called the Cardinals victory.

Featured Cardinals Insider

ARI

Arizona Cardinals

ARI +1

Over 45

Cardinals 27, 49ers 20

“Cardinals quarterback Kyler Murray will throw for 300 yards and three touchdowns in a big divisional win. He will likely have his mobility limited to some degree, which will lead to him throwing the ball”...

November 5, 2021 via espn.com

Featured Cardinals Insider
Blake Murphy

Blake Murphy

Revenge of the Birds

SF

Arizona Cardinals

ARI +2.5

Under 44.5

November 6, 2021

Featured Cardinals Insider
Jess Root

Jess Root

Sportsbook Wire

ARI

Arizona Cardinals

ARI +2.5

Under 44.5

November 6, 2021

Swipe left to see more expert picks


San Francisco 49ers

What 49ers Insiders Said

0% of team insiders called the Cardinals victory.

Featured 49ers Insider

SF

San Francisco 49ers

SF -1

Under 45

49ers 23, Cardinals 20

“These teams met less than a month ago, but a lot has changed on both sides. Cardinals QB Kyler Murray and receiver DeAndre Hopkins are dealing with injuries, receiver A.J. Green is on the COVID-19 list and defensive end J.J. Watt is out for the season. The Niners, meanwhile, expect to have kicker Robbie Gould and tight end George Kittle back from their injuries, and quarterback Jimmy Garoppolo will be available this time around. The first meeting was decided by seven points, and this one should be similarly close, with the team that handles attrition better being the likely winner.”...

November 5, 2021 via espn.com

Featured 49ers Insider
Alex Byrne

Alex Byrne

Fourth and Nine

SF

San Francisco 49ers

SF -2.5

Under 45.5

November 5, 2021

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Top-Ranked Expert Picks

Best performing analysts in each category this season.

49ers Overall Experts

Pete Sweeney

40-19-1 (68%)

ARI

Frank T. Raines

39-21-0 (65%)

SF

Christopher Dunnells

33-15-0 (69%)

ARI
49ers Moneyline Experts

Jess Root

16-4-0 (80%)

ARI

Jeremy Fowler

15-5-0 (75%)

SF

Pete Sweeney

16-4-0 (80%)

ARI
49ers Spread Experts

Frank T. Raines

16-4-0 (80%)

SF -0.5

Emmanuel Morgan

15-4-1 (79%)

ARI +1

Craig Miller

14-5-1 (74%)

ARI +0.5
49ers Over/Under Experts

Andrew Reid

14-4-0 (78%)

Under 45.5

Gregg Rosenthal

10-2-0 (83%)

Under 46

Christopher Dunnells

12-4-0 (75%)

Over 45.5
Cardinals Overall Experts

Michael Regan

23-5-0 (82%)

ARI

John Whiticar

36-18-0 (67%)

ARI

Aaron Casey

31-20-0 (61%)

ARI
Cardinals Moneyline Experts

Michael Regan

12-2-0 (86%)

ARI

Ron Kopp

11-6-0 (65%)

SF

J Andrews

10-7-0 (59%)

SF
Cardinals Spread Experts

Michael Regan

11-3-0 (79%)

ARI +3.5

HC Green

13-5-0 (72%)

ARI -1.5

Aaron Casey

12-5-0 (71%)

ARI -1.5
Cardinals Over/Under Experts

John Whiticar

13-5-0 (72%)

Over 44.5

Michael Flores

9-2-0 (82%)

Over 43.5

Frank T. Raines

12-5-0 (71%)

Over 46.5

Top-Ranked Staff Consensus Picks

Consensus staff picks from the best performing outlets this season.

ESPN

316-304-4 (51%)

Matchup Performance

ARI (69%)Moneyline
ARI +5.5 (50%)Spread
Over 44.5 (50%)Total
NFL Network

242-225-0 (52%)

Matchup Performance

ARI (55%)Moneyline
ARI +5.5 (100%)Spread
No O/U PicksTotal
CBS Sports

295-305-0 (49%)

Matchup Performance

ARI (25%)Moneyline
ARI +5.5 (25%)Spread
No O/U PicksTotal
USA Today Sports

297-234-1 (56%)

Matchup Performance

ARI (71%)Moneyline
ARI +5.5 (57%)Spread
No O/U PicksTotal