Los Angeles Rams

LAR

Los Angeles Rams

10

31

SF

San Francisco 49ers

San Francisco 49ers

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Media Consensus Picks

267 PicksMoneyline
San Francisco 49ers

SF

+145

5%

5% predicted the 49ers to win.

229 PicksSpread
San Francisco 49ers

SF +3.5

-105

13%

13% predicted the 49ers to cover the spread.

117 PicksOver/Under

Under 50.5

-110

43%

43% predicted the score to be under 50.5.

Best Sportsbook Odds


What National Media Said

8% of national media analysts called the 49ers victory.

Featured National Media Analyst

LAR

Los Angeles Rams

LAR -4

Over 49

Rams 32, 49ers 24

“Watch for the Rams to dial up the passing game and for quarterback Matthew Stafford -- coming off his worst outing of the season -- to pass for more than 350 yards and three touchdowns. The 49ers' defense has defended the pass well (206.5 passing yards allowed per game, fourth-best in the NFL) but has allowed an average of 25.3 points per game (No. 25). Coach Sean McVay and the Rams have lost four straight to division-rival San Francisco, and their last meeting in 2020 ended with McVay publicly expressing his frustration with now former quarterback Jared Goff. McVay does not want to lose five straight to his friend Kyle Shanahan”...

November 11, 2021 via espn.com

Featured National Media Analyst

LAR

Los Angeles Rams

LAR -4

Over 49

Rams 34, 49ers 20

“The 49ers' defense just got torched by Arizona's backup offense, so what's going to happen against a loaded and presumably angry Rams offense coming off a disappointing loss? Considering that the Niners are 30th in the league in QBR allowed (88.6) and 31st in yards allowed per attempt (10.3) when opposing offenses use empty formations, and the Rams go empty more than any other team in the league, the Niners had better come up with some answers in a hurry. Otherwise, their best bet is winning a shootout, something they haven't proved capable of this season”...

November 11, 2021 via espn.com

Featured National Media Analyst
Gregg Rosenthal

Gregg Rosenthal

NFL Network

LAR

San Francisco 49ers

SF +4

Rams 27, 49ers 24

“Shanahan's four-game winning streak over the Rams is one of the best bullet points on his increasingly scrutinized résumé. The San Francisco coach knows that time is running shorter on this season and he can't play Jimmy Garoppolo if the losing continues. Jimmy G's improved play over the last two weeks -- in addition to the return of George Kittle and the uptick in Brandon Aiyuk's performance -- should give the 49ers reason to believe this game is winnable. Matthew Stafford only needs a C+ game from his offensive line, however, to have enough time to find mismatches throughout San Francisco's depleted secondary. If Shanahan's recent mastery of Sean McVay is gone, too, what will be left for the Niners?”...

November 11, 2021 via nfl.com

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Los Angeles Rams

What Rams Insiders Said

0% of team insiders called the 49ers victory.

Featured Rams Insider

LAR

Los Angeles Rams

LAR -4

Over 49

Rams 32, 49ers 24

“Watch for the Rams to dial up the passing game and for quarterback Matthew Stafford -- coming off his worst outing of the season -- to pass for more than 350 yards and three touchdowns. The 49ers' defense has defended the pass well (206.5 passing yards allowed per game, fourth-best in the NFL) but has allowed an average of 25.3 points per game (No. 25). Coach Sean McVay and the Rams have lost four straight to division-rival San Francisco, and their last meeting in 2020 ended with McVay publicly expressing his frustration with now former quarterback Jared Goff. McVay does not want to lose five straight to his friend Kyle Shanahan”...

November 11, 2021 via espn.com

Featured Rams Insider
Cameron DaSilva

Cameron DaSilva

Sportsbook Wire

LAR

Los Angeles Rams

LAR -4

Over 49

November 11, 2021

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San Francisco 49ers

What 49ers Insiders Said

50% of team insiders called the 49ers victory.

Featured 49ers Insider

LAR

Los Angeles Rams

LAR -4

Over 49

Rams 34, 49ers 20

“The 49ers' defense just got torched by Arizona's backup offense, so what's going to happen against a loaded and presumably angry Rams offense coming off a disappointing loss? Considering that the Niners are 30th in the league in QBR allowed (88.6) and 31st in yards allowed per attempt (10.3) when opposing offenses use empty formations, and the Rams go empty more than any other team in the league, the Niners had better come up with some answers in a hurry. Otherwise, their best bet is winning a shootout, something they haven't proved capable of this season”...

November 11, 2021 via espn.com

Featured 49ers Insider
Alex Byrne

Alex Byrne

Fourth and Nine

SF

San Francisco 49ers

SF +3.5

Over 48.5

November 9, 2021

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Top-Ranked Expert Picks

Best performing analysts in each category this season.

49ers Overall Experts

Pete Sweeney

40-19-1 (68%)

LAR

Frank T. Raines

39-21-0 (65%)

LAR

Christopher Dunnells

33-15-0 (69%)

LAR
49ers Moneyline Experts

Jess Root

16-4-0 (80%)

SF

Jeremy Fowler

15-5-0 (75%)

SF

Pete Sweeney

16-4-0 (80%)

LAR
49ers Spread Experts

Frank T. Raines

16-4-0 (80%)

LAR -3.5

Emmanuel Morgan

15-4-1 (79%)

LAR -4

Craig Miller

14-5-1 (74%)

LAR -3.5
49ers Over/Under Experts

Andrew Reid

14-4-0 (78%)

Under 48.5

Christopher Dunnells

12-4-0 (75%)

Under 48.5

Brendan O'Bryan

13-5-0 (72%)

Over 48.5
Rams Overall Experts

Sterling Furrowh

39-12-0 (76%)

LAR

Kevin Nogle

45-18-0 (71%)

LAR

Ryan Harris

36-12-0 (75%)

LAR
Rams Moneyline Experts

Kevin Nogle

18-3-0 (86%)

LAR

Alex Byrne

8-2-0 (80%)

SF

Will Brinson

17-4-0 (81%)

SF
Rams Spread Experts

HC Green

17-4-0 (81%)

SF +3.5

J Andrews

16-5-0 (76%)

SF +3.5

Ryan Harris

13-3-0 (81%)

LAR -3.5
Rams Over/Under Experts

Sterling Furrowh

14-3-0 (82%)

Under 48.5

Kyle Silagyi

15-5-0 (75%)

Over 48.5

Seth Baker

11-2-0 (85%)

Under 48.5

Top-Ranked Staff Consensus Picks

Consensus staff picks from the best performing outlets this season.

ESPN

425-329-2 (56%)

Matchup Performance

SF (6%)Moneyline
SF -3.5 (0%)Spread
No O/U PicksTotal
ProFootballTalk

89-72-0 (55%)

Matchup Performance

SF (0%)Moneyline
SF -3.5 (0%)Spread
No O/U PicksTotal
NFL Network

313-213-0 (60%)

Matchup Performance

SF (0%)Moneyline
SF +3.5 (100%)Spread
No O/U PicksTotal
USA Today Sports

350-223-1 (61%)

Matchup Performance

SF (14%)Moneyline
SF +3.5 (29%)Spread
No O/U PicksTotal